Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922387 | 0.91 | MAPT (0.50) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8920748 | 0.90 | KMT2A (0.44) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8921264 | 0.84 | CYP4F2 (0.47) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8921973 | 0.84 | KMT2A (0.39) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8921852 | 0.84 | POLB (0.44) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8919875 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8923389 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1LMNAHSP90AA1 | |
| SCHEMBL8924828 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8921188 | 0.77 | KMT2A (0.46) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL8920108 | 0.77 | RAB9A (0.46) | ALDH1A1KMT2AMAPTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |