Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920108 | 0.85 | RAB9A (0.46) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8921606 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8922901 | 0.82 | MAPT (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8783999 | 0.82 | POLB (0.55) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8922387 | 0.81 | MAPT (0.50) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8921264 | 0.80 | CYP4F2 (0.47) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8923079 | 0.80 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8920748 | 0.80 | KMT2A (0.44) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8924835 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNAKDM4EALOX15 | |
| SCHEMBL8921187 | 0.80 | MEN1 (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |