Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920687 | 0.91 | CCKBR (0.38) | CCKBRPLA2G10PLA2G5KMT2ARAMP1 | |
| SCHEMBL8919489 | 0.89 | L3MBTL1 (0.37) | CCKBRPLA2G10PLA2G5MAPTKMT2A | |
| SCHEMBL8920178 | 0.88 | CCKBR (0.46) | CCKBRPLA2G10PLA2G5 | |
| SCHEMBL8924391 | 0.88 | CCKBR (0.39) | CCKBRPLA2G10PLA2G5NPC1TP53 | |
| SCHEMBL8922568 | 0.87 | MAPT (0.32) | CCKBRNPC1TP53MAPTRAB9A | |
| SCHEMBL8926039 | 0.87 | DRD2 (0.32) | CCKBRNPC1TP53MAPTRAB9A | |
| SCHEMBL8920349 | 0.84 | RAMP1 (0.42) | CCKBRPLA2G10PLA2G5NPC1TP53 | |
| SCHEMBL8922067 | 0.84 | PLA2G10 (0.43) | CCKBRPLA2G10PLA2G5 | |
| SCHEMBL8920807 | 0.81 | CCKBR (0.37) | CCKBRPLA2G10PLA2G5MAPTRAB9A | |
| SCHEMBL8921440 | 0.80 | PLA2G10 (0.40) | CCKBRPLA2G10PLA2G5RAMP1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643904-A | Substituted hexahdryoazepinones and tetrahydrobenzazepinones | PFIZER INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5484917-A | FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY | PFIZER INC. (US) | 1996-01-16 | — | — | US | disclosed |