SCHEMBL8920935

SCHEMBL8920935

COc1ccc2c(c1)C1(NC2=N)OC(C)O1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
PDE7A Q13946 1/20 0.35
PDK2 Q15119 1/20 0.34
NQO1 P15559 2/20 0.33
POR P16435 2/20 0.33
AKR1B1 P15121 2/20 0.33
ACHE P22303 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2E1 P05181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP4B1 P13584 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918904 0.89 ACHE (0.36) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL8918299 0.85 PDK2 (0.38) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL8920583 0.83 PDK2 (0.40) ALDH1A1MEN1MAPTKMT2APDK2
SCHEMBL8920932 0.81 PDE7A (0.38) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL8919366 0.79 PDK2 (0.34) PDK2
SCHEMBL8919192 0.77 NPC1 (0.31) ALDH1A1
SCHEMBL7817179 0.75 MEN1 (0.40) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL7816525 0.75 ALDH1A1 (0.31) ALDH1A1MAPT
SCHEMBL8920322 0.74 ALDH1A1 (0.38) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL8921050 0.73 MAOB (0.40) MAPTPDK2ACHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed