SCHEMBL8921186

SCHEMBL8921186

CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(O)c(N)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.64
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
MAPK1 P28482 2/20 0.60
ALDH1A1 P00352 2/20 0.60
LMNA P02545 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
ALOX15 P16050 1/20 0.60
HTT P42858 1/20 0.60
RAB9A P51151 1/20 0.57
GAA P10253 1/20 0.57
GFER P55789 1/20 0.57
KDM4E B2RXH2 2/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8921185 0.92 MEN1 (0.60) PKMMEN1KMT2AMAPK1ALDH1A1
SCHEMBL8920534 0.87 PKM (0.67) PKMMEN1KMT2AALDH1A1LMNA
SCHEMBL8920527 0.85 KDM4E (0.59) PKMMEN1KMT2AALDH1A1LMNA
SCHEMBL22066232 0.83 PKM (0.77) PKMMEN1KMT2AMAPK1ALDH1A1
SCHEMBL4055616 0.82 TDP1 (0.57) PKMMEN1KMT2AALDH1A1LMNA
SCHEMBL7834756 0.81 LMNA (0.66) PKMMEN1KMT2AMAPK1ALDH1A1
SCHEMBL29118884 0.81 PKM (0.73) PKMMEN1KMT2AMAPK1ALDH1A1
SCHEMBL8016507 0.81 GAA (0.69) PKMMEN1KMT2AALDH1A1LMNA
Hydrochloric Acid SCHEMBL11740154 0.80 TDP1 (0.55) PKMMEN1KMT2AALDH1A1LMNA
SCHEMBL9997237 0.80 APAF1 (0.67) PKMMEN1KMT2AMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5668259-A ANIONIC DYES CLARIANT FINANCE (BVI) LIMITED (VG) 1997-09-16 US disclosed