Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 6/20 | 0.38 |
| ▸ | RXRB | P28702 | 6/20 | 0.38 |
| ▸ | RXRG | P48443 | 5/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 3/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.34 |
| ▸ | GLRB | P48167 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098875 | 0.80 | ASPH (0.44) | LDHARXRARXRBRXRGASPH | |
| SCHEMBL29404413 | 0.80 | ASPH (0.44) | LDHARXRARXRBRXRGASPH | |
| Water SCHEMBL25435119 | 0.78 | ASPH (0.43) | LDHARXRARXRBRXRGASPH | |
| SCHEMBL28053969 | 0.77 | RXRA (0.41) | RXRARXRBRXRGASPHGLRA3 | |
| SCHEMBL22114832 | 0.77 | ASPH (0.40) | RXRARXRBRXRGASPHKMO | |
| SCHEMBL3369693 | 0.77 | CES2 (0.48) | RXRARXRBRXRGASPHCES2 | |
| SCHEMBL4171508 | 0.75 | EPRS1 (0.43) | ASPHGLRA3GLRBDAOCES2 | |
| SCHEMBL8037245 | 0.74 | ASPH (0.40) | RXRARXRBRXRGASPHCES2 | |
| SCHEMBL1101352 | 0.72 | ASPH (0.37) | LDHARXRARXRBRXRGASPH | |
| SCHEMBL28155006 | 0.72 | ASPH (0.37) | RXRARXRBASPHGLRA3GLRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |