Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20447205 | 0.86 | ALDH1A1 (0.54) | ATMANPEPTAS1R3TAS1R1HTT | |
| SCHEMBL25252107 | 0.73 | SMN1; SMN2 (0.57) | HTTALDH1A1SMN1; SMN2TDP1YAP1 | |
| SCHEMBL13396259 | 0.73 | SMN1; SMN2 (0.57) | HTTALDH1A1SMN1; SMN2TDP1YAP1 | |
| SCHEMBL18997618 | 0.73 | SMN1; SMN2 (0.68) | HTTALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL26618380 | 0.71 | ALDH1A1 (0.49) | HTTALDH1A1SMN1; SMN2TDP1BMP1 | |
| SCHEMBL26618376 | 0.71 | ALDH1A1 (0.49) | HTTALDH1A1SMN1; SMN2TDP1BMP1 | |
| SCHEMBL4573265 | 0.71 | ALDH1A1 (0.41) | HTTALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL4573275 | 0.71 | ALDH1A1 (0.41) | HTTALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL7363231 | 0.70 | LDHA (0.50) | ANPEPHTTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7363227 | 0.70 | LDHA (0.50) | ANPEPHTTALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624928-A | Method of synthesizing an endonuclease inhibitor and analogs thereof | MERCK & CO., INC. (US) | 1997-04-29 | — | — | US | disclosed |