Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922095 | 0.84 | MAPT (0.35) | LMNAPOLBMAPTTP53 | |
| SCHEMBL8921928 | 0.83 | ALDH1A1 (0.45) | LMNAPOLBMAPTHTTTSHR | |
| SCHEMBL8922762 | 0.80 | MALT1 (0.48) | LMNAPOLBMAPTMALT1MAOB | |
| SCHEMBL8922729 | 0.75 | MALT1 (0.49) | LMNAPOLBMAPTMALT1MAOB | |
| SCHEMBL8922106 | 0.67 | MCHR1 (0.35) | POLBMAPTTP53 | |
| SCHEMBL3861313 | 0.66 | L3MBTL1 (0.48) | LMNAPOLBMAPTHTT | |
| SCHEMBL7439824 | 0.64 | TP53 (0.47) | MAOBTP53 | |
| SCHEMBL8922100 | 0.62 | KMT2A (0.38) | LMNAPOLBMAPT | |
| SCHEMBL2741659 | 0.62 | NISCH (0.42) | MAOBTP53 | |
| SCHEMBL8921377 | 0.62 | ALDH1A1 (0.46) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |