Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922100 | 0.85 | KMT2A (0.38) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL8922762 | 0.82 | MALT1 (0.48) | MALT1ACLYLMNAPOLBMAPT | |
| SCHEMBL8922733 | 0.75 | LMNA (0.42) | MALT1ACLYLMNAPOLBMAPT | |
| SCHEMBL8921188 | 0.72 | KMT2A (0.46) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL8921372 | 0.71 | RAB9A (0.46) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL7456883 | 0.71 | ALDH1A1 (0.53) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL7453231 | 0.70 | SMN1; SMN2 (0.47) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL7458969 | 0.69 | MAPT (0.49) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL7462906 | 0.68 | MAPT (0.51) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL8921973 | 0.68 | KMT2A (0.39) | LMNAMAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |