Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.33 |
| ▸ | SPR | P35270 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | APOB | P04114 | 1/20 | 0.32 |
| ▸ | MTTP | P55157 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922733 | 0.84 | LMNA (0.42) | MAPTPOLBTP53LMNA | |
| SCHEMBL8922106 | 0.78 | MCHR1 (0.35) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8921928 | 0.74 | ALDH1A1 (0.45) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8922100 | 0.74 | KMT2A (0.38) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3861313 | 0.68 | L3MBTL1 (0.48) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8922762 | 0.67 | MALT1 (0.48) | MAPTPOLBMTNR1ATP53LMNA | |
| SCHEMBL2480890 | 0.66 | MTNR1A (0.47) | PPARGMTNR1AMTNR1B | |
| SCHEMBL2597095 | 0.65 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL8921377 | 0.63 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL8921195 | 0.63 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |