Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543383 | 0.77 | ALDH1A1 (0.47) | LMNAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6512953 | 0.77 | PDE10A (0.60) | CYP1A2CYP2C9POLBPDE10ACYP2C19 | |
| SCHEMBL29940575 | 0.77 | PDE10A (0.60) | CYP1A2CYP2C9POLBPDE10ACYP2C19 | |
| SCHEMBL8564839 | 0.77 | CYP1A2 (0.37) | CYP1A2CYP2C9POLBPDE10ACYP2C19 | |
| SCHEMBL924608 | 0.76 | TDP2 (0.44) | CYP1A2CYP2C19MEN1KMT2APAX8 | |
| SCHEMBL1563360 | 0.74 | TDP2 (0.42) | CYP1A2CYP2C19MEN1KMT2APAX8 | |
| SCHEMBL8568460 | 0.74 | MEN1 (0.35) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7841891 | 0.72 | PDE10A (0.55) | CYP1A2CYP2C9POLBPDE10ACYP2C19 | |
| SCHEMBL28020680 | 0.71 | LMNA (0.49) | CYP1A2CYP2C9POLBPDE10ACYP2C19 | |
| SCHEMBL8563304 | 0.71 | HTT (0.39) | CYP1A2CYP2C9POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |