SCHEMBL8923370

SCHEMBL8923370

CC(C)(C)[Si](C)(C)n1nnnc1C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.31
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8923623 0.71 HCAR3 (0.40) HCAR3
SCHEMBL3671626 0.67
SCHEMBL29027809 0.66 ALDH1A1 (0.34) HCAR3NPC1
SCHEMBL20128067 0.66 MAPK1 (0.33) NPC1
Ammonia Solution, Strong SCHEMBL4751250 0.65 LMNA (0.30)
SCHEMBL507145 0.63
SCHEMBL31402456 0.63
SCHEMBL28976472 0.62 HCAR3 (0.42) HCAR3NPC1
SCHEMBL6581481 0.60 FAAH (0.36)
SCHEMBL28712647 0.60 HSD17B10 (0.43) HCAR3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5597929-A Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran SUMITOMO CHEMICAL CO., LTD. (JP) 1997-01-28 US disclosed
EP-0716088-A1 PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-12 EP disclosed