Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227355 | 0.77 | PI4KA (0.37) | ADORA1ADORA3ADORA2AP2RY1 | |
| SCHEMBL6402247 | 0.76 | ADORA1 (0.39) | P2RY12ADORA1ADORA3ADORA2A | |
| SCHEMBL8923627 | 0.76 | PRMT6 (0.36) | PRMT6P2RY12ADORA1BMPR1BP2RY2 | |
| SCHEMBL2290374 | 0.72 | TRPM2 (0.56) | — | |
| SCHEMBL8332514 | 0.72 | PRMT6 (0.33) | PRMT6P2RY12ADORA1ADORA3ADORA2A | |
| SCHEMBL7863923 | 0.71 | PRMT6 (0.35) | PRMT6P2RY12ADORA1ADORA3ADORA2A | |
| SCHEMBL8958836 | 0.70 | PRMT6 (0.34) | PRMT6ADORA1ADORA3ADORA2A | |
| SCHEMBL9155260 | 0.70 | PRMT6 (0.45) | PRMT6P2RY12ADORA1P2RY1 | |
| SCHEMBL9155270 | 0.70 | PRMT6 (0.45) | PRMT6P2RY12ADORA1P2RY1 | |
| SCHEMBL8937135 | 0.70 | ADORA1 (0.34) | PRMT6P2RY12ADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470967-A | Hybridization probes to detect nucleic acid sequences | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0517796-B1 | OLIGONUCLEOTIDE ANALOGS | DU PONT MERCK PHARMA (US) | 1995-04-19 | — | — | EP | disclosed |