Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28712647 | 0.81 | HSD17B10 (0.43) | CYP1A2ALDH1A1HPGDMAPK1LMNA | |
| SCHEMBL6948864 | 0.76 | NPC1 (0.48) | ALDH1A1MAPK1LMNARAB9ANPC1 | |
| SCHEMBL4142949 | 0.76 | ALDH1A1 (0.47) | CYP1A2HSD11B1ALDH1A1HPGDMAPK1 | |
| SCHEMBL9111798 | 0.75 | HCAR3 (0.46) | HPGD | |
| SCHEMBL8925425 | 0.74 | GHSR (0.41) | HSD11B1HPGDMAPK1TSHRERCC5 | |
| SCHEMBL6580324 | 0.73 | MAPK1 (0.42) | ALDH1A1MAPK1LMNAERCC5FEN1 | |
| SCHEMBL6579797 | 0.72 | MAPK1 (0.38) | HSD11B1ALDH1A1HPGDMAPK1TSHR | |
| SCHEMBL6951940 | 0.72 | TRPV1 (0.44) | ALDH1A1HPGDMAPK1NPC1KMT2A | |
| SCHEMBL8921457 | 0.72 | MAPK1 (0.53) | CYP1A2HSD11B1ALDH1A1MAPK1LMNA | |
| SCHEMBL11271744 | 0.72 | HPGD (0.53) | ALDH1A1HPGDMAPK1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |