Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107793 | 0.87 | TAS1R3 (0.47) | TAS1R3TAS1R1KMT2AMEN1MAPT | |
| SCHEMBL8768942 | 0.87 | KMT2A (0.57) | TAS1R3TAS1R1KMT2AMEN1MAPT | |
| SCHEMBL8926604 | 0.83 | POLB (0.56) | KMT2AMEN1MAPTTSHRABCB11 | |
| SCHEMBL8768817 | 0.81 | MAPT (0.55) | TAS1R3TAS1R1KMT2AMEN1MAPT | |
| SCHEMBL9233473 | 0.76 | KMT2A (0.60) | TAS1R3TAS1R1KMT2AMEN1MAPT | |
| SCHEMBL8924202 | 0.75 | TSHR (0.47) | TAS1R3TAS1R1KMT2AMAPTALDH1A1 | |
| SCHEMBL8768099 | 0.74 | TSHR (0.52) | TAS1R3TAS1R1MAPTALDH1A1TSHR | |
| SCHEMBL8767887 | 0.73 | PPARA (0.43) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL8768174 | 0.73 | ALDH1A1 (0.56) | TAS1R3TAS1R1KMT2AMEN1MAPT | |
| SCHEMBL9111522 | 0.73 | ALDH1A1 (0.54) | TAS1R3TAS1R1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |