SCHEMBL8924475

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3138307	0.90	LMNA (0.67)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL8915591	0.89	ALDH1A1 (0.67)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL12315667	0.88	LMNA (0.64)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL12315668	0.88	KMT2A (0.66)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL8914869	0.86	ALDH1A1 (0.72)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL8925693	0.84	ALDH1A1 (0.75)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL14218026	0.83	TRPV1 (0.61)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL9987888	0.83	ALDH1A1 (0.69)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL8917255	0.83	ALDH1A1 (0.76)	LMNAALDH1A1POLBKDM4ETDP1
	SCHEMBL12453308	0.83	ALDH1A1 (0.59)	LMNAALDH1A1POLBKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.