Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399314 | 0.81 | KMT2A (0.55) | HTR2CHTR2AKMT2ANISCHKDM4E | |
| SCHEMBL28219132 | 0.78 | HTR2C (0.45) | HTR2CHTR2AALOX12L3MBTL1TDP1 | |
| SCHEMBL16371569 | 0.76 | ALDH1A1 (0.35) | KMT2ATDP1LMNAALDH1A1HSD17B10 | |
| SCHEMBL9444559 | 0.75 | ESR1 (0.54) | L3MBTL1KDM4EGAAHPGDALDH1A1 | |
| SCHEMBL7644288 | 0.75 | TLR8 (0.55) | HTR2CHTR2AKMT2AALDH1A1 | |
| SCHEMBL18010784 | 0.74 | ALDH1A1 (0.43) | L3MBTL1TDP1KDM4EHPGDLMNA | |
| SCHEMBL11046318 | 0.74 | ALDH1A1 (0.55) | KMT2AL3MBTL1TDP1PDE4BGAA | |
| SCHEMBL5486071 | 0.72 | HTR2C (0.66) | HTR2CHTR2AKMT2AL3MBTL1NISCH | |
| SCHEMBL7027182 | 0.71 | L3MBTL1 (0.39) | L3MBTL1KDM4EGAAHPGDNPC1 | |
| SCHEMBL19961723 | 0.70 | HTR2C (0.46) | HTR2CHTR2AL3MBTL1NISCHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5676884-A | Nonlinear optical materials containing polar disulfone-functionalized molecules | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-10-14 | — | — | US | disclosed |
| US-5578251-A | NONLINEAR-OPTICAL RESPONSE; ALKYLATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5360582-A | Compositions with polymers for light sensitive elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| EP-0594697-A1 | NONLINEAR OPTICAL MATERIALS CONTAINING POLAR DISULFONE-FUNCTIONALIZED MOLECULES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993002383-A1 | NONLINEAR OPTICAL MATERIALS CONTAINING POLAR DISULFONE-FUNCTIONALIZED MOLECULES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-02-04 | — | — | WO | disclosed |