Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101512 | 0.81 | HPGD (0.47) | MEN1KMT2A | |
| SCHEMBL12935252 | 0.77 | MAPT (0.40) | MEN1KMT2A | |
| Perchlorate SCHEMBL2057139 | 0.76 | HPGD (0.42) | MEN1KMT2A | |
| SCHEMBL12934729 | 0.72 | HPGD (0.52) | MEN1KMT2ALMNA | |
| SCHEMBL13984874 | 0.69 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL10049175 | 0.69 | KDM1A (0.46) | LMNA | |
| SCHEMBL11848984 | 0.68 | TGM2 (0.44) | PDCD1CD274ACHEMEN1KMT2A | |
| SCHEMBL2036237 | 0.68 | L3MBTL1 (0.54) | ACHEMEN1KMT2ALMNA | |
| SCHEMBL2005219 | 0.67 | GAA (0.41) | MEN1KMT2ALMNA | |
| SCHEMBL8390740 | 0.67 | CA2 (0.40) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5667764-A | USEFUL IN TREATMENT OF POST-ANGIOPLASTY RESTENOSIS, RHEUMATOID ARTHRITIS, TUMOR CELL PROLIFERATION AND PSORIASIS | ZYNAXIS, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0643706-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR BINDING BIO-AFFECTING SUBSTANCES TO SURFACE MEMBRANES OF BIO-PARTICLES | Zynaxis Inc. (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0643706-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR BINDING BIO-AFFECTING SUBSTANCES TO SURFACE MEMBRANES OF BIO-PARTICLES. | ZYNAXIS INC (US) | 1994-12-27 | — | — | EP | disclosed |
| WO-1993011120-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR BINDING BIO-AFFECTING SUBSTANCES TO SURFACE MEMBRANES OF BIO-PARTICLES | ZYNAXIS TECHNOLOGIES, INCORPORATED (US) | 1993-06-10 | — | — | WO | disclosed |