Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928102 | 0.86 | MTNR1B (0.55) | MTNR1BMTNR1A | |
| SCHEMBL8928098 | 0.84 | MTNR1A (0.63) | MTNR1A | |
| SCHEMBL8928245 | 0.83 | MTNR1A (0.56) | MTNR1BMTNR1A | |
| SCHEMBL14430371 | 0.78 | POLB (0.61) | MTNR1BMTNR1A | |
| SCHEMBL29032167 | 0.77 | MTNR1A (0.64) | MTNR1BMTNR1A | |
| SCHEMBL8031017 | 0.76 | MTNR1A (0.86) | MTNR1BMTNR1A | |
| SCHEMBL27446239 | 0.76 | SMN1; SMN2 (0.81) | MTNR1BMTNR1A | |
| SCHEMBL793987 | 0.76 | GLA (0.63) | MTNR1BMTNR1A | |
| SCHEMBL19304105 | 0.76 | CHRM2 (0.54) | MTNR1BMTNR1A | |
| SCHEMBL12524034 | 0.76 | TAAR1 (0.54) | MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | claimed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |