Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928212 | 0.86 | MTNR1A (0.70) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8928099 | 0.83 | MTNR1B (0.73) | MTNR1AMTNR1B | |
| SCHEMBL8928102 | 0.81 | MTNR1B (0.55) | MTNR1AMTNR1BKDM4EHSD17B10 | |
| SCHEMBL8021679 | 0.79 | MTNR1A (0.87) | MTNR1AMTNR1B | |
| SCHEMBL8928098 | 0.79 | MTNR1A (0.63) | MTNR1A | |
| SCHEMBL8928226 | 0.78 | MTNR1A (0.70) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8928078 | 0.74 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL20920062 | 0.74 | EPHX2 (0.76) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14430371 | 0.73 | POLB (0.61) | MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL8643878 | 0.73 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | claimed |
| US-5698101-A | Hollow fiber membranes | MEMTEC LIMITED (AU) | 1997-12-16 | — | — | US | disclosed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5395570-A | Hollow fibre membrane extrusion | MEMTEC LIMITED (AU) | 1995-03-07 | — | — | US | disclosed |
| US-5318417-A | Extrusion head for forming polymeric hollow fiber | SIEMENS WATER TECHNOLOGIES CORP. | 1994-06-07 | — | — | US | disclosed |
| EP-0423249-B1 | EXTRUSION OF HOLLOW FIBRE MEMBRANES | MEMTEC LTD (AU) | 1994-03-23 | — | — | EP | disclosed |
| EP-0408688-B1 | POROUS MEMBRANES | MEMTEC LTD (AU) | 1994-03-23 | — | — | EP | disclosed |
| US-5277851-A | Removing surfactant from polyolefin fiber | MEMTEC LIMITED (AU) | 1994-01-11 | — | — | US | disclosed |
| EP-0423249-A4 | EXTRUSION OF HOLLOW FIBRE MEMBRANES | — | 1991-05-22 | — | — | EP | disclosed |
| EP-0423249-A1 | EXTRUSION OF HOLLOW FIBRE MEMBRANES. | MEMTEC LTD (AU) | 1991-04-24 | — | — | EP | disclosed |
| EP-0408688-A4 | POROUS MEMBRANES | — | 1991-04-17 | — | — | EP | disclosed |
| EP-0408688-A1 | POROUS MEMBRANES. | MEMTEC LTD (AU) | 1991-01-23 | — | — | EP | disclosed |
| WO-1990005007-A1 | POROUS MEMBRANES | MEMTEC LIMITED (AU) | 1990-05-17 | — | — | WO | disclosed |
| WO-1990005006-A1 | EXTRUSION OF HOLLOW FIBRE MEMBRANES | MEMTEC LIMITED (AU) | 1990-05-17 | — | — | WO | disclosed |