Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.70 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928245 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8021679 | 0.80 | MTNR1A (0.87) | MTNR1AMTNR1B | |
| SCHEMBL8928239 | 0.80 | KMT2A (0.65) | ALDH1A1MAPTTSHR | |
| SCHEMBL3346293 | 0.79 | ALDH1A1 (0.57) | MTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL8803860 | 0.79 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL8928226 | 0.79 | MTNR1A (0.70) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8928115 | 0.79 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL23576456 | 0.76 | ALDH1A1 (0.61) | MTNR1AMTNR1BALDH1A1MAPTTSHR | |
| SCHEMBL32671561 | 0.76 | ALDH1A1 (0.61) | MTNR1AMTNR1BALDH1A1MAPTTSHR | |
| SCHEMBL27678559 | 0.75 | MTNR1A (0.54) | MTNR1AMTNR1BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |