SCHEMBL8928213

SCHEMBL8928213

NCCN(CCN)C(=O)CCCCC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
CYP2D6 P10635 1/20 0.36
NFKB1 P19838 1/20 0.36
ALDH1A1 P00352 3/20 0.35
ACHE P22303 1/20 0.35
MC5R P33032 2/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
BLM P54132 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
THRB P10828 2/20 0.34
PLG P00747 1/20 0.34
ALOX15 P16050 1/20 0.34
SLC6A2 P23975 1/20 0.34
RECQL P46063 1/20 0.34
SLC6A3 Q01959 1/20 0.34
MC3R P41968 2/20 0.34
MC4R P32245 1/20 0.34
PAOX Q6QHF9 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8928215 0.98 LMNA (0.38) LMNACYP2D6NFKB1ALDH1A1ACHE
SCHEMBL19723211 0.86 ACHE (0.41) LMNACYP2D6NFKB1ALDH1A1ACHE
Hydrochloric Acid SCHEMBL17373887 0.85 BLM (0.45) LMNACYP2D6NFKB1ALDH1A1ACHE
SCHEMBL25163063 0.84 LMNA (0.38) LMNACYP2D6NFKB1ALDH1A1ACHE
SCHEMBL20528875 0.84 NFKB1 (0.56) LMNACYP2D6NFKB1ALDH1A1KMT2A
SCHEMBL1905343 0.82 LMNA (0.39) LMNAALDH1A1KMT2AMEN1HPGD
SCHEMBL2401560 0.81 CYP2D6 (0.44) LMNACYP2D6NFKB1ALDH1A1ACHE
SCHEMBL9452878 0.81 CES2 (0.46) LMNAALDH1A1KMT2AMEN1ALOX15
SCHEMBL19091931 0.80 LMNA (0.36) LMNACYP2D6NFKB1ALDH1A1ACHE
SCHEMBL7564703 0.80 LMNA (0.38) LMNAALDH1A1ACHEKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673309-B1 REACTIVE SOLS AND METHOD FOR PRODUCING THEM PERFORMANCE CHEMICALS HANDELS GMBH (DE) 2015-03-18 EP disclosed
EP-2673309-A1 REACTIVE SOLS AND METHOD FOR PRODUCING THEM Performance Chemicals Handels GmbH (DE) 2013-12-18 EP disclosed
WO-2012095517-A1 REACTIVE SOLS AND METHOD FOR PRODUCING THEM PERFORMANCE CHEMICALS HANDELS GMBH (DE) 2012-07-19 WO disclosed
EP-0495269-B1 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK & CHEMICALS (JP) 1997-03-05 EP disclosed
US-5292833-A Polyepoxide compound, carbamate compound and catalyst DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-03-08 US disclosed
WO-1992012192-A2 THERMOSETTING REACTIVE RESIN MIXTURE, MOULDED ARTICLE AND COATING MADE THEREFROM DAINIPPON INK & CHEMICALS, INC. (JP) 1992-07-23 WO disclosed
EP-0495269-A2 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-07-22 EP disclosed