SCHEMBL8928215

SCHEMBL8928215

NCCN(CCN)C(=O)CCCCCCCCC(N)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.38
PLG P00747 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
SLC6A2 P23975 1/20 0.38
RECQL P46063 1/20 0.38
SLC6A3 Q01959 1/20 0.38
ACHE P22303 1/20 0.37
PAOX Q6QHF9 1/20 0.37
SOAT1 P35610 2/20 0.35
FAAH O00519 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8928213 0.98 LMNA (0.39) LMNAMEN1KMT2AALDH1A1PLG
SCHEMBL19723211 0.84 ACHE (0.41) LMNAMEN1KMT2AALDH1A1PLG
SCHEMBL9452878 0.83 CES2 (0.46) LMNAMEN1KMT2AALDH1A1ALOX15
Hydrochloric Acid SCHEMBL17373887 0.83 BLM (0.45) LMNAMEN1KMT2AALDH1A1PLG
SCHEMBL25163063 0.83 LMNA (0.38) LMNAMEN1KMT2AALDH1A1PLG
SCHEMBL20528875 0.83 NFKB1 (0.56) LMNAMEN1KMT2AALDH1A1PLG
SCHEMBL2149157 0.83 LMNA (0.38) LMNAMEN1KMT2AALDH1A1SOAT1
SCHEMBL27538272 0.80 KDM5A (0.45) MEN1KMT2AALDH1A1ALOX15ACHE
SCHEMBL1905343 0.80 LMNA (0.39) LMNAMEN1KMT2AALDH1A1SOAT1
SCHEMBL2401560 0.79 CYP2D6 (0.44) LMNAMEN1KMT2AALDH1A1PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0495269-B1 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK & CHEMICALS (JP) 1997-03-05 EP disclosed
US-5292833-A Polyepoxide compound, carbamate compound and catalyst DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-03-08 US disclosed
WO-1992012192-A2 THERMOSETTING REACTIVE RESIN MIXTURE, MOULDED ARTICLE AND COATING MADE THEREFROM DAINIPPON INK & CHEMICALS, INC. (JP) 1992-07-23 WO disclosed
EP-0495269-A2 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-07-22 EP disclosed