Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928258 | 0.84 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA | |
| SCHEMBL8928234 | 0.84 | GRK6 (0.43) | ALDH1A1KDM4EHPGDGRK6HTT | |
| SCHEMBL6137231 | 0.81 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA | |
| SCHEMBL6137171 | 0.79 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA | |
| SCHEMBL6137339 | 0.77 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA | |
| SCHEMBL6137255 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA | |
| SCHEMBL6137213 | 0.74 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA | |
| SCHEMBL6137355 | 0.74 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA | |
| SCHEMBL8918577 | 0.70 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA | |
| SCHEMBL6137173 | 0.70 | AR (0.57) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755931-A1 | Dihydropyridine and pyridine derivatives and process for their preparation | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-01-29 | — | — | EP | claimed |
| EP-0755931-A1 | Dihydropyridine and pyridine derivatives and process for their preparation | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-01-29 | — | — | EP | disclosed |