Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 6/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 3/20 | 0.36 |
| ▸ | DNER | Q8NFT8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928586 | 0.85 | OPRK1 (0.51) | OPRK1GABRA1GABRA5GABRA2GABRB2 | |
| SCHEMBL9038947 | 0.85 | BRD4 (0.50) | OPRK1HPGDBRD4GABRA1GABRA5 | |
| SCHEMBL8928600 | 0.80 | OPRK1 (0.47) | OPRK1HPGDBRD4GABRA1GABRA5 | |
| SCHEMBL8928425 | 0.77 | MAPK1 (0.44) | OPRK1HPGDBRD4KMT2ARECQL | |
| SCHEMBL2539664 | 0.76 | BRD4 (0.54) | OPRK1HPGDBRD4GABRA1GABRA5 | |
| SCHEMBL8928633 | 0.76 | OPRK1 (0.58) | OPRK1HPGDBRD4GABRA1GABRA5 | |
| SCHEMBL2538162 | 0.76 | BRD4 (0.45) | OPRK1BRD4PDE4DPTAFRDNER | |
| SCHEMBL8928945 | 0.76 | OPRK1 (0.44) | OPRK1HPGDBRD4GABRA1GABRA5 | |
| SCHEMBL8928620 | 0.76 | SMN1; SMN2 (0.40) | HPGDBRD4MEN1KMT2ARECQL | |
| SCHEMBL8928404 | 0.76 | HPGD (0.41) | OPRK1HPGDBRD4LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |