Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 6/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928531 | 0.90 | HPGD (0.41) | RAB9ASMN1; SMN2CCKBRAKT1MAPT | |
| SCHEMBL8928511 | 0.89 | PKM (0.42) | PKMMAPK1RAB9ACASRSMN1; SMN2 | |
| SCHEMBL8928656 | 0.88 | OPRK1 (0.44) | PKMMAPK1RAB9ACASRSMN1; SMN2 | |
| SCHEMBL8928389 | 0.85 | PKM (0.41) | PKMMAPK1RAB9ACASRSMN1; SMN2 | |
| SCHEMBL8928500 | 0.80 | MAPK1 (0.43) | MAPK1RAB9ACASRSMN1; SMN2CCKBR | |
| SCHEMBL8928635 | 0.80 | PTAFR (0.44) | PKMMAPK1RAB9ACASRSMN1; SMN2 | |
| SCHEMBL8928437 | 0.80 | HPGD (0.41) | RAB9ASMN1; SMN2CCKBRAKT1MAPT | |
| SCHEMBL8928545 | 0.79 | OPRK1 (0.47) | MAPT | |
| SCHEMBL8928504 | 0.79 | OPRK1 (0.56) | PKMMAPK1RAB9AKMT2A | |
| SCHEMBL8928465 | 0.78 | OPRK1 (0.47) | RAB9ASMN1; SMN2CCKBRAKT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |