Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966882 | 1.00 | LOXL2 (0.55) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| SCHEMBL3451201 | 0.85 | LOXL2 (0.58) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| SCHEMBL29365671 | 0.84 | LOXL2 (0.56) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| SCHEMBL31336079 | 0.84 | LOXL2 (0.56) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| SCHEMBL49270 | 0.84 | LOXL2 (0.56) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| SCHEMBL3120573 | 0.82 | MTNR1A (0.60) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| SCHEMBL630523 | 0.82 | SIRT1 (0.64) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| Water SCHEMBL30025993 | 0.82 | LOXL2 (0.55) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| SCHEMBL31511816 | 0.82 | LOXL2 (0.55) | LOXL2NLRP3MTNR1AMTNR1BFLT3 | |
| SCHEMBL3447317 | 0.82 | LOXL2 (0.55) | LOXL2NLRP3MTNR1AMTNR1BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-4563464-A | 2-Azabicyclo(2.2.2)octane derivatives and their use as immunosuppressive agents | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1986-01-07 | — | — | US | disclosed |
| EP-0132964-A2 | 2-Azabicyclo[2.2.2]octane derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1985-02-13 | — | — | EP | disclosed |