Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 9/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928667 | 0.95 | OPRK1 (0.44) | OPRK1PDE4DMEN1KMT2ACCKAR | |
| SCHEMBL8928440 | 0.92 | OPRK1 (0.55) | OPRK1PDE4DMEN1KMT2ACCKAR | |
| SCHEMBL8928668 | 0.91 | PTAFR (0.38) | OPRK1PDE4DMEN1KMT2ACCKAR | |
| SCHEMBL8928631 | 0.87 | MEN1 (0.39) | OPRK1MEN1KMT2ACCKARPTAFR | |
| SCHEMBL8928869 | 0.84 | L3MBTL1 (0.36) | MEN1KMT2ACCKARPTAFRCYP3A4 | |
| SCHEMBL8928748 | 0.84 | OPRK1 (0.42) | OPRK1PDE4DMEN1KMT2ACCKAR | |
| SCHEMBL8928544 | 0.80 | OPRK1 (0.52) | OPRK1PDE4DMEN1KMT2APTAFR | |
| SCHEMBL8928672 | 0.79 | OPRK1 (0.43) | OPRK1PDE4DMEN1KMT2ACCKAR | |
| SCHEMBL8928766 | 0.76 | OPRK1 (0.42) | OPRK1PDE4DMEN1KMT2ACCKAR | |
| SCHEMBL8689792 | 0.76 | KMT2A (0.38) | OPRK1PDE4DMEN1KMT2ACCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |