Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928668 | 0.87 | PTAFR (0.38) | L3MBTL1MEN1KMT2ACCKARBRD4 | |
| SCHEMBL8928631 | 0.84 | MEN1 (0.39) | L3MBTL1MEN1KMT2ACCKARBRD4 | |
| SCHEMBL8928732 | 0.84 | OPRK1 (0.44) | L3MBTL1MEN1KMT2ACCKARBRD4 | |
| SCHEMBL8928876 | 0.83 | MEN1 (0.37) | L3MBTL1MEN1KMT2ACCKARBRD4 | |
| SCHEMBL8928667 | 0.80 | OPRK1 (0.44) | MEN1KMT2ACCKARBRD4LMNA | |
| SCHEMBL8928440 | 0.78 | OPRK1 (0.55) | MEN1KMT2ACCKARCYP3A4PTAFR | |
| SCHEMBL8928429 | 0.76 | MEN1 (0.35) | MEN1KMT2ABRD4ALDH1A1CYP1A2 | |
| SCHEMBL8689291 | 0.73 | MEN1 (0.39) | L3MBTL1MEN1KMT2ACCKARBRD4 | |
| SCHEMBL9038947 | 0.71 | BRD4 (0.50) | BRD4LMNAPTAFRGABRA1GABRA5 | |
| SCHEMBL8928678 | 0.70 | MEN1 (0.39) | L3MBTL1MEN1KMT2ACCKARBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |