Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931277 | 0.84 | MAPT (0.40) | ALDH1A1SLC6A4SLC6A9HTR1A | |
| SCHEMBL8722264 | 0.79 | SLC6A9 (0.61) | ACHESLC6A4SLC6A9HTR1A | |
| SCHEMBL4377909 | 0.73 | CYP2D6 (0.51) | ALDH1A1SLC6A4SLC6A9 | |
| Oxalic Acid SCHEMBL11350914 | 0.71 | SLC6A4 (0.57) | SLC6A4SLC6A9 | |
| SCHEMBL9501079 | 0.70 | SLC6A4 (0.61) | SLC6A4SLC6A9HTR1A | |
| SCHEMBL6499305 | 0.70 | SLC6A9 (0.52) | ALDH1A1SMN1; SMN2SLC6A9 | |
| SCHEMBL8341049 | 0.70 | SLC6A4 (0.51) | SLC6A4 | |
| SCHEMBL5268496 | 0.70 | SLC6A9 (0.63) | SLC6A4SLC6A9 | |
| SCHEMBL8726597 | 0.70 | SLC6A9 (0.57) | ACHESLC6A4SLC6A9HTR1A | |
| SCHEMBL18375503 | 0.69 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2GAAACHESLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618968-A | N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation | PLIVA FARMACEUTSKA KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 1997-04-08 | — | — | US | disclosed |