Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931267 | 0.84 | ALDH1A1 (0.44) | SLC6A9SLC6A4HTR1AALDH1A1 | |
| SCHEMBL8931276 | 0.75 | SLC6A4 (0.64) | SLC6A9SLC6A4HRH3HTR1AMEN1 | |
| SCHEMBL8341049 | 0.74 | SLC6A4 (0.51) | SLC6A4HRH3KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4803483 | 0.71 | SLC6A4 (0.62) | SLC6A4HRH3MEN1KMT2ACYP1A2 | |
| SCHEMBL9501079 | 0.70 | SLC6A4 (0.61) | SLC6A9SLC6A4HRH3HTR1A | |
| Oxalic Acid SCHEMBL11350914 | 0.66 | SLC6A4 (0.57) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL6499305 | 0.66 | SLC6A9 (0.52) | MAPTSLC6A9MEN1ALDH1A1KMT2A | |
| SCHEMBL11347429 | 0.65 | SLC6A9 (0.48) | SLC6A9SLC6A4HRH3L3MBTL1ALDH1A1 | |
| SCHEMBL18660127 | 0.65 | MAPT (0.77) | MAPTCRHBPCRHR2MMP14L3MBTL1 | |
| SCHEMBL11357415 | 0.65 | CHRNB2 (0.57) | SLC6A9SLC6A4HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618968-A | N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation | PLIVA FARMACEUTSKA KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 1997-04-08 | — | — | US | disclosed |