Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.64 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726521 | 0.86 | SLC6A9 (0.63) | SLC6A4HRH3SLC6A9HTR1ASLC6A2 | |
| SCHEMBL8722264 | 0.84 | SLC6A9 (0.61) | SLC6A4HRH3SLC6A9HTR1ASLC6A2 | |
| SCHEMBL8726597 | 0.81 | SLC6A9 (0.57) | SLC6A4HRH3SLC6A9HTR1ASLC6A2 | |
| SCHEMBL9501079 | 0.81 | SLC6A4 (0.61) | SLC6A4HRH3SLC6A9HTR1A | |
| SCHEMBL679320 | 0.79 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL29700710 | 0.79 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL3415108 | 0.78 | SLC6A4 (0.78) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL11350914 | 0.77 | SLC6A4 (0.57) | SLC6A4HRH3SLC6A9 | |
| SCHEMBL5570738 | 0.77 | SLC6A4 (0.81) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| SCHEMBL8971141 | 0.77 | SLC6A4 (0.81) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618968-A | N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation | PLIVA FARMACEUTSKA KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 1997-04-08 | — | — | US | disclosed |