Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | DAPK2 | Q9UIK4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036105 | 0.72 | NOTUM (0.61) | HPGDALDH1A1NOTUMKDM4EMEN1 | |
| SCHEMBL8181951 | 0.71 | CNR1 (0.49) | HPGDALDH1A1KDM4EALOX15MEN1 | |
| SCHEMBL20769916 | 0.71 | RAB9A (0.54) | HPGDALDH1A1NOTUMKDM4EMEN1 | |
| SCHEMBL31039610 | 0.71 | RAB9A (0.54) | HPGDALDH1A1NOTUMKDM4EMEN1 | |
| SCHEMBL8181303 | 0.68 | ALDH1A1 (0.43) | HPGDALDH1A1KDM4EALOX15MEN1 | |
| SCHEMBL8931383 | 0.67 | ALDH1A1 (0.41) | HPGDALDH1A1KDM4EALOX15MEN1 | |
| SCHEMBL29569233 | 0.63 | CACNA1H (0.55) | HPGDALDH1A1SMOKDM4EALOX15 | |
| SCHEMBL6185686 | 0.63 | DAPK3 (0.48) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL17608164 | 0.63 | LRRK2 (0.51) | HPGDALDH1A1NOTUMNPC1RAB9A | |
| SCHEMBL19991900 | 0.63 | CTNNB1 (0.57) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013512-A1 | N-[2-SUBSTITUTED-3-(2-AMINOETHYL)-1H-INDOL-5-YL]-AMIDES: NEW 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |