Sugi Predict

Sugi Predict / Compounds / SCHEMBL8932050

SCHEMBL8932050

SCHEMBL8932050

C[Si](C)(C)c1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 1/20 0.46
▸ NR1H3 Q13133 1/20 0.46
▸ ACHE P22303 2/20 0.45
▸ NPC1 O15118 3/20 0.40
▸ RAB9A P51151 3/20 0.40
▸ IDO1 P14902 3/20 0.38
▸ TDO2 P48775 1/20 0.38
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ CA7 P43166 1/20 0.38
▸ CA9 Q16790 1/20 0.38
▸ NFE2L2 Q16236 1/20 0.35
▸ NOTUM Q6P988 1/20 0.34
▸ ORAI1 Q96D31 1/20 0.33
▸ ORAI2 Q96SN7 1/20 0.33
▸ ORAI3 Q9BRQ5 1/20 0.33
▸ TRPV6 Q9H1D0 1/20 0.33
▸ CES2 O00748 1/20 0.33
▸ CES1 P23141 1/20 0.33
▸ LOXL2 Q9Y4K0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20636767 0.85 KCNH3 (0.43) NPC1RAB9ASMN1; SMN2
SCHEMBL20172779 0.83 APP (0.41) NR1H2NR1H3ACHENPC1RAB9A
SCHEMBL586534 0.83 NR1H2 (0.50) NR1H2NR1H3ACHESCN5A
SCHEMBL26548156 0.80 PGR (0.47) NPC1RAB9AIDO1TDO2CA2
SCHEMBL26548515 0.80 PGR (0.47) NPC1RAB9AIDO1TDO2CA2
SCHEMBL26548134 0.80 PGR (0.47) NPC1RAB9AIDO1TDO2CA2
SCHEMBL3160463 0.79 ACHE (0.43) ACHENPC1RAB9AIDO1TDO2
SCHEMBL26548657 0.78 PGR (0.46) NPC1RAB9AIDO1TDO2CA9
SCHEMBL26548672 0.78 PGR (0.46) NPC1RAB9AIDO1TDO2CA9
SCHEMBL24624085 0.77 ACHE (0.41) ACHENPC1RAB9AIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 — — US disclosed
CN-119560635-A Electrolyte, secondary injection liquefaction forming method and lithium ion battery 江苏正力新能电池技术股份有限公司 2025-03-04 — — CN disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 — — US disclosed
CN-115010726-B Cage compound, intermediate thereof, preparation method and application thereof 中国科学院上海有机化学研究所 2024-08-16 — — CN disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 — — US disclosed
US-20230292592-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
US-11542621-B1 Coatings and coated surfaces including low-surface energy inorganic particles MAXTERIAL, INC. (US) 2023-01-03 — — US disclosed
CN-115010726-A Cage-shaped compound, intermediate thereof, preparation method and application thereof 中国科学院上海有机化学研究所 2022-09-06 — — CN disclosed
CN-107459438-B Novel practical nonmetal-catalyzed silica-based deprotection method 台州学院 2020-09-01 — — CN disclosed
EP-3691894-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM Maxterial, Inc. (US) 2020-08-12 — — EP disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 — — US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 — — US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 — — US disclosed
CN-1043575-C Silylated acetylcholinesterase inhibitors MERRELL DOW PHARMA (US) 1999-06-09 — — CN disclosed
EP-0684951-B1 SILYLATED ACETYLCHOLINESTERASE INHIBITORS MERRELL PHARMA INC (US) 1997-05-07 — — EP disclosed
US-5523442-A TREATING ALZHEIMER'S, DEMENTIA MERRELL PHARMACEUTICALS INC. (US) 1996-06-04 — — US disclosed
CN-1117733-A Silylated acetylcholinesterase inhibitors MERRELL DOW PHARMA (US) 1996-02-28 — — CN disclosed
EP-0684951-A1 SILYLATED ACETYLCHOLINESTERASE INHIBITORS. MERRELL DOW PHARMA (US) 1995-12-06 — — EP disclosed
WO-1994019356-A1 SILYLATED ACETYLCHOLINESTERASE INHIBITORS MERRELL DOW PHARMACEUTICALS INC. (US) 1994-09-01 — — WO disclosed
EP-0611769-A1 Silylated acetylcholinesterase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1994-08-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 NR1H2 412/4885NR1H3 238/4885ACHE 4428/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 NR1H2 412/4885NR1H3 238/4885ACHE 4428/4885
US-20230292592-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP NR1H2 111/4885NR1H3 66/4885ACHE 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.