Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18013200 | 0.74 | LRRK2 (0.36) | L3MBTL1KDM4EMAPTFABP4 | |
| SCHEMBL9004994 | 0.73 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL9005135 | 0.73 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL8932234 | 0.72 | KMT2A (0.49) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL9005068 | 0.69 | CYP11B1 (0.38) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL8932284 | 0.69 | TGFBR1 (0.41) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL8932310 | 0.69 | MAPT (0.50) | L3MBTL1KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL9005032 | 0.68 | RAB9A (0.42) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL8932318 | 0.68 | PKM (0.43) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL9005129 | 0.66 | HDAC1 (0.40) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |