SCHEMBL9017625

SCHEMBL9017625

CCNC(=O)c1c(N)ccc(Cl)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 2/20 0.49
NOS2 P35228 1/20 0.43
LMNA P02545 3/20 0.41
KDM4E B2RXH2 3/20 0.40
ALOX15 P16050 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
P2RX7 Q99572 1/20 0.38
BRAF P15056 1/20 0.38
HDAC1 Q13547 1/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
DRD2 P14416 1/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
HSP90AB1 P08238 1/20 0.37
POLB P06746 1/20 0.36
THRB P10828 1/20 0.36
RECQL P46063 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017618 0.87 L3MBTL1 (0.51) PRKCZNOS2LMNAKDM4EALOX15
SCHEMBL20050668 0.87 PRKCZ (0.49) PRKCZNOS2LMNAKDM4EALOX15
SCHEMBL30739840 0.87 PRKCZ (0.49) PRKCZNOS2LMNAKDM4EALOX15
SCHEMBL9017600 0.85 PRKCZ (0.42) PRKCZNOS2LMNAKDM4EALOX15
SCHEMBL8932345 0.80 P2RX7 (0.57) PRKCZP2RX7ALDH1A1POLBHPGD
SCHEMBL11657258 0.80 PRKCZ (0.46) PRKCZNOS2LMNAKDM4EALOX15
SCHEMBL7218880 0.78 PRKCZ (0.45) PRKCZNOS2LMNAKDM4ESMN1; SMN2
SCHEMBL7224593 0.78 PRKCZ (0.41) PRKCZLMNAKDM4EALOX15ALDH1A1
SCHEMBL2450664 0.76 THRB (0.40) LMNAKDM4EALOX15SMN1; SMN2ALDH1A1
SCHEMBL8527175 0.75 PRKCZ (0.40) PRKCZNOS2LMNAKDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0749416-A1 SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS MONSANTO COMPANY (US) 1996-12-27 EP disclosed
WO-1995024380-A1 SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS MONSANTO COMPANY (US) 1995-09-14 WO disclosed