SCHEMBL30739840

SCHEMBL30739840

CCNC(=O)c1c(Cl)ccc(N)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 2/20 0.49
KDM4E B2RXH2 3/20 0.40
NOS2 P35228 1/20 0.40
LMNA P02545 4/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
P2RX7 Q99572 1/20 0.38
BRAF P15056 1/20 0.38
HDAC1 Q13547 1/20 0.38
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
ALOX15 P16050 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
JAK2 O60674 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20050668 1.00 PRKCZ (0.49) PRKCZKDM4ENOS2LMNASMN1; SMN2
SCHEMBL4593067 0.87 L3MBTL1 (0.48) PRKCZKDM4ELMNASMN1; SMN2ALDH1A1
SCHEMBL9017625 0.87 PRKCZ (0.49) PRKCZKDM4ENOS2LMNASMN1; SMN2
SCHEMBL7218880 0.81 PRKCZ (0.45) PRKCZKDM4ENOS2LMNASMN1; SMN2
SCHEMBL8527175 0.81 PRKCZ (0.40) PRKCZKDM4ENOS2LMNAALDH1A1
SCHEMBL20050671 0.81 SLC6A2 (0.42) PRKCZKDM4ELMNASMN1; SMN2ALDH1A1
SCHEMBL30739918 0.81 SLC6A2 (0.42) PRKCZKDM4ELMNASMN1; SMN2ALDH1A1
SCHEMBL8932345 0.80 P2RX7 (0.57) PRKCZALDH1A1HPGDP2RX7JAK2
SCHEMBL11657258 0.80 PRKCZ (0.46) PRKCZKDM4ENOS2LMNASMN1; SMN2
SCHEMBL20051092 0.80 PTGS2 (0.43) LMNASMN1; SMN2ALDH1A1HPGDP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed