Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.63 |
| ▸ | CTSS | P25774 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KYNU | Q16719 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932367 | 0.90 | CTSL (0.62) | CTSLCTSSATMBACE1CTSK | |
| SCHEMBL1760460 | 0.87 | KYNU (0.59) | CTSLCTSSALDH1A1THRBCYP2C9 | |
| SCHEMBL6826924 | 0.87 | KYNU (0.59) | CTSLCTSSALDH1A1THRBCYP2C9 | |
| SCHEMBL6831659 | 0.87 | KYNU (0.59) | CTSLCTSSALDH1A1THRBCYP2C9 | |
| SCHEMBL2256830 | 0.87 | KYNU (0.64) | CTSLCTSSATMALDH1A1THRB | |
| SCHEMBL345230 | 0.87 | KYNU (0.64) | CTSLCTSSATMALDH1A1THRB | |
| SCHEMBL345229 | 0.87 | KYNU (0.64) | CTSLCTSSATMALDH1A1THRB | |
| SCHEMBL4561049 | 0.85 | CTSK (0.59) | CTSLCTSSALDH1A1THRBCYP2C9 | |
| SCHEMBL4560701 | 0.85 | CTSK (0.59) | CTSLCTSSALDH1A1THRBCYP2C9 | |
| SCHEMBL8557434 | 0.85 | CTSK (0.59) | CTSLCTSSALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996027370-A1 | FREE RADICAL SCAVENGER MOLECULES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-09-12 | — | — | WO | disclosed |