SCHEMBL345229

SCHEMBL345229

COC(=O)[C@@H](CO)NC(=O)OCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KYNU Q16719 1/20 0.64
ALDH1A1 P00352 2/20 0.62
ALOX15 P16050 1/20 0.62
CTSK P43235 5/20 0.58
CTSS P25774 4/20 0.56
CTSL P07711 3/20 0.56
CTSB P07858 3/20 0.56
TRPM8 Q7Z2W7 1/20 0.55
THRB P10828 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TACR1 P25103 2/20 0.54
CTRB1 P17538 2/20 0.54
ATM Q13315 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2256830 1.00 KYNU (0.64) KYNUALDH1A1ALOX15CTSKCTSS
SCHEMBL345230 1.00 KYNU (0.64) KYNUALDH1A1ALOX15CTSKCTSS
SCHEMBL6831659 0.94 KYNU (0.59) KYNUALDH1A1ALOX15CTSKCTSS
SCHEMBL1760460 0.94 KYNU (0.59) KYNUALDH1A1ALOX15CTSKCTSS
SCHEMBL6826924 0.94 KYNU (0.59) KYNUALDH1A1ALOX15CTSKCTSS
SCHEMBL8053250 0.91 CTSL (0.65) ALDH1A1ALOX15CTSKCTSSCTSL
SCHEMBL2677964 0.91 CTSK (0.57) KYNUALDH1A1ALOX15CTSKCTSS
SCHEMBL7032185 0.91 CTSK (0.57) KYNUALDH1A1ALOX15CTSKCTSS
SCHEMBL17446717 0.91 CTSK (0.57) KYNUALDH1A1ALOX15CTSKCTSS
SCHEMBL13503284 0.89 ALDH1A1 (0.64) KYNUALDH1A1ALOX15CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-9657057-B2 Dipeptide and tripeptide epoxy ketone protease inhibitors ONYX THERAPEUTICS, INC. (US) 2017-05-23 US disclosed
EP-3144295-A1 PROCESS FOR THE PREPARATION OF LACOSAMIDE Divi's Laboratories Limited (IN) 2017-03-22 EP disclosed
US-20160229830-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES BIOMARIN PHARMACEUTICAL INC. 2016-08-11 US disclosed
US-20160229830-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES BIOMARIN PHARMACEUTICAL INC. 2016-08-11 US disclosed
CN-102378752-A Improved method for manufacturing dipeptidyl peptidase-iv inhibitor and intermediate DONG A PHARM CO LTD 2012-03-14 CN disclosed
EP-2415754-A2 IMPROVED METHOD FOR MANUFACTURING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE Dong-A Pharmaceutical Co., Ltd. (KR) 2012-02-08 EP disclosed
US-20120016126-A1 METHOD FOR MANUFACTURING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE DONG-A PHARMACEUTICAL. CO., LTD (KR) 2012-01-19 US disclosed
US-7888351-B2 Organic compounds NOVARTIS AG (CH) 2011-02-15 US disclosed
US-20110034462-A1 ORGANIC COMPOUNDS BAESCHLIN DANIEL KASPAR 2011-02-10 US disclosed
US-20090281069-A1 ORGANIC COMPOUNDS BAESCHLIN DANIEL KASPAR 2009-11-12 US disclosed
EP-2007723-A2 ORGANIC COMPOUNDS Novartis AG (CH) 2008-12-31 EP disclosed
WO-2007115821-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2007-10-18 WO disclosed
US-5618808-A Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists PFIZER, INC. (US) 1997-04-08 US disclosed
WO-1994001421-A1 BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS PFIZER INC. (US) 1994-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016126-A1 METHOD FOR MANUFACTURING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE DPP4, DPP3, DPP7 KYNU 1618/4885ALDH1A1 752/4885ALOX15 3707/4885
US-20160229830-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES GBA1, UGCG, GBA2 KYNU 3685/4885ALDH1A1 1342/4885ALOX15 490/4885
US-20090281069-A1 ORGANIC COMPOUNDS OTC, OAT, SLCO2B1 KYNU 746/4885ALDH1A1 72/4885ALOX15 194/4885
US-20110034462-A1 ORGANIC COMPOUNDS OTC, OAT, SLCO2B1 KYNU 746/4885ALDH1A1 72/4885ALOX15 194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.