Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932570 | 0.84 | GAA (0.39) | BCHEACHETSHRSMN1; SMN2 | |
| SCHEMBL8932463 | 0.81 | NAAA (0.40) | CRBNSMN1; SMN2IDO1 | |
| SCHEMBL8932546 | 0.81 | CRBN (0.44) | BCHEACHECRBNAPPIDO1 | |
| SCHEMBL8932477 | 0.80 | MAOB (0.40) | CRBNAPPIDO1 | |
| SCHEMBL8932404 | 0.78 | IDO1 (0.38) | CRBNSMN1; SMN2IDO1 | |
| SCHEMBL8932409 | 0.78 | APP (0.42) | TSHRCRBNAPPSMN1; SMN2IDO1 | |
| SCHEMBL8932562 | 0.78 | GSK3B (0.37) | TSHRAPPIDO1 | |
| SCHEMBL8932509 | 0.78 | TP53 (0.40) | CRBNAPPSMN1; SMN2IDO1 | |
| SCHEMBL8932452 | 0.76 | EPHX1 (0.40) | ACHETSHRSMN1; SMN2 | |
| SCHEMBL9202656 | 0.76 | TSHR (0.46) | TSHRCRBNAPPIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |