Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932562 | 0.83 | GSK3B (0.37) | APPLMNAIDO1ALDH1A1 | |
| SCHEMBL8932411 | 0.78 | BCHE (0.39) | APPCRBNSMN1; SMN2IDO1 | |
| SCHEMBL8932477 | 0.78 | MAOB (0.40) | APPCRBNIDO1ALDH1A1MAOA | |
| SCHEMBL8932463 | 0.77 | NAAA (0.40) | CRBNSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8932546 | 0.76 | CRBN (0.44) | APPCRBNLMNAIDO1HSD17B10 | |
| SCHEMBL8932409 | 0.76 | APP (0.42) | TP53APPCRBNSMN1; SMN2IDO1 | |
| SCHEMBL8932570 | 0.75 | GAA (0.39) | SMN1; SMN2MEN1KMT2AMAPTLMNA | |
| SCHEMBL8932452 | 0.74 | EPHX1 (0.40) | TP53NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8932404 | 0.74 | IDO1 (0.38) | CRBNSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8932476 | 0.73 | APP (0.44) | TP53APPCRBNSMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |