Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932424 | 0.89 | KMT2A (0.47) | KMT2AALDH1A1SMN1; SMN2THRBTSHR | |
| SCHEMBL8932463 | 0.85 | NAAA (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8932404 | 0.82 | IDO1 (0.38) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL8932570 | 0.79 | GAA (0.39) | KMT2AMEN1ALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL8932411 | 0.76 | BCHE (0.39) | SMN1; SMN2ACHETSHR | |
| SCHEMBL8932546 | 0.75 | CRBN (0.44) | ACHE | |
| SCHEMBL8932509 | 0.74 | TP53 (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8932477 | 0.74 | MAOB (0.40) | ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL8932409 | 0.73 | APP (0.42) | ALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8932562 | 0.72 | GSK3B (0.37) | ALDH1A1L3MBTL1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |