Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932404 | 0.87 | IDO1 (0.38) | NAAASMN1; SMN2CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL8932452 | 0.85 | EPHX1 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8932411 | 0.81 | BCHE (0.39) | SMN1; SMN2IDO1CRBN | |
| SCHEMBL8932424 | 0.81 | KMT2A (0.47) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8932546 | 0.80 | CRBN (0.44) | LMNAIDO1HSD17B10CRBN | |
| SCHEMBL8932570 | 0.79 | GAA (0.39) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8932477 | 0.79 | MAOB (0.40) | NAAAALDH1A1CYP2C9IDO1CRBN | |
| SCHEMBL8932409 | 0.77 | APP (0.42) | SMN1; SMN2ALDH1A1IDO1CYP3A4CRBN | |
| SCHEMBL8932509 | 0.77 | TP53 (0.40) | SMN1; SMN2ALDH1A1LMNAMAPK1MEN1 | |
| SCHEMBL8932562 | 0.77 | GSK3B (0.37) | ALDH1A1LMNAIDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |