Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932561 | 0.71 | APP (0.36) | PKMNPC1RAB9ALMNATP53 | |
| SCHEMBL8932465 | 0.70 | NPC1 (0.40) | PKMNPC1RAB9ALMNATP53 | |
| SCHEMBL8932491 | 0.70 | LMNA (0.39) | GAALMNATP53TSHRSMN1; SMN2 | |
| SCHEMBL9201486 | 0.67 | MAPT (0.39) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL8932546 | 0.67 | CRBN (0.44) | LMNA | |
| SCHEMBL8932409 | 0.67 | APP (0.42) | GAATP53TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL899315 | 0.66 | SMN1; SMN2 (0.64) | PKMNPC1RAB9AMGAMGAA | |
| SCHEMBL8932416 | 0.66 | OPRK1 (0.37) | PKMNPC1RAB9ALMNATP53 | |
| SCHEMBL15011086 | 0.66 | SMN1; SMN2 (0.66) | PKMNPC1RAB9AMGAMGAA | |
| SCHEMBL9202656 | 0.65 | TSHR (0.46) | GAALMNATSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |