Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932452 | 0.89 | EPHX1 (0.40) | KMT2ATHRBTSHRSMN1; SMN2USP2 | |
| SCHEMBL8932463 | 0.81 | NAAA (0.40) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8932404 | 0.78 | IDO1 (0.38) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8932509 | 0.73 | TP53 (0.40) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8932562 | 0.73 | GSK3B (0.37) | KDM4ETSHRGAAALDH1A1 | |
| SCHEMBL8932411 | 0.72 | BCHE (0.39) | TSHRSMN1; SMN2 | |
| SCHEMBL8932546 | 0.71 | CRBN (0.44) | — | |
| SCHEMBL8932570 | 0.70 | GAA (0.39) | KMT2AKDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL8932477 | 0.70 | MAOB (0.40) | ALDH1A1 | |
| SCHEMBL1557112 | 0.70 | ALDH1A1 (0.50) | KMT2AKDM4ETHRBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |