Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808944 | 0.79 | MAPT (0.42) | MAPTMEN1KMT2ATAAR1CTSS | |
| SCHEMBL5792443 | 0.69 | TACR1 (0.35) | MAPTMEN1KMT2ATAAR1TSHR | |
| SCHEMBL3439003 | 0.68 | SRC (0.37) | CYP3A4CTSSCTSK | |
| SCHEMBL21985331 | 0.66 | PTGS2 (0.48) | PTGS2MAPTMEN1KMT2ATAAR1 | |
| SCHEMBL19638102 | 0.65 | PTGS2 (0.42) | PTGS2CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9938243 | 0.64 | CTSS (0.46) | CTSSCTSK | |
| SCHEMBL14831425 | 0.64 | CTSK (0.52) | ACECTSSCTSK | |
| SCHEMBL14831426 | 0.64 | CTSK (0.52) | ACECTSSCTSK | |
| SCHEMBL27732865 | 0.63 | PTGS2 (0.43) | PTGS2NPC1LMNAMAPTCASP3 | |
| Biphenyl SCHEMBL27794837 | 0.63 | TDP1 (0.62) | PTGS2NPC1LMNAMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |