Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477139 | 0.81 | F2 (0.47) | PRSS1F2 | |
| SCHEMBL8723763 | 0.78 | PRSS1 (0.42) | DGAT1PRSS1TMPRSS15ALDH1A1F2 | |
| SCHEMBL6475958 | 0.75 | F2 (0.62) | F2 | |
| SCHEMBL6484948 | 0.74 | DPP4 (0.40) | DGAT1ALDH1A1 | |
| SCHEMBL6484032 | 0.73 | PRSS1 (0.38) | DGAT1PRSS1TMPRSS15LTA4HALDH1A1 | |
| SCHEMBL7702747 | 0.72 | DGAT1 (0.39) | DGAT1PRSS1TMPRSS15ALDH1A1F2 | |
| SCHEMBL8722619 | 0.71 | F2 (0.40) | DGAT1F2 | |
| SCHEMBL6476434 | 0.71 | OPRM1 (0.46) | DGAT1PRSS1TMPRSS15ALDH1A1F2 | |
| SCHEMBL8725887 | 0.70 | F2 (0.40) | PRSS1F2 | |
| SCHEMBL7705659 | 0.65 | F2 (0.33) | DGAT1PRSS1TMPRSS15ALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |