Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933305 | 0.80 | SMN1; SMN2 (0.48) | MTNR1AMTNR1BALDH1A1KDM4ETACR1 | |
| SCHEMBL6601868 | 0.77 | TACR1 (0.45) | ALDH1A1KDM4ETACR1ATMCYP2D6 | |
| SCHEMBL8933307 | 0.72 | HPGD (0.38) | ALDH1A1KDM4ETACR1ATMEPHX1 | |
| SCHEMBL218878 | 0.67 | MMP2 (0.73) | MMP2EPHX1 | |
| SCHEMBL2876751 | 0.67 | MMP2 (0.73) | MMP2EPHX1 | |
| SCHEMBL218877 | 0.67 | MMP2 (0.73) | MMP2EPHX1 | |
| SCHEMBL6600320 | 0.67 | ALDH1A1 (0.42) | ALDH1A1ATMTSHRHTTMEN1 | |
| Hydrochloric Acid SCHEMBL23051768 | 0.66 | MMP2 (0.71) | MMP2EPHX1 | |
| Hydrochloric Acid SCHEMBL23051769 | 0.66 | MMP2 (0.71) | MMP2EPHX1 | |
| SCHEMBL2636331 | 0.65 | TRPA1 (0.50) | MTNR1AMTNR1BMMP2NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |