Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933302 | 0.80 | MTNR1A (0.43) | CYP1A2CYP2D6TACR1ATMKDM4E | |
| SCHEMBL6601868 | 0.74 | TACR1 (0.45) | SMN1; SMN2PKMCYP2D6NPSR1TACR1 | |
| SCHEMBL8933307 | 0.72 | HPGD (0.38) | SMN1; SMN2PKMCYP2D6TACR1ATM | |
| SCHEMBL29188177 | 0.72 | CYP1A2 (0.50) | SMN1; SMN2CYP1A2PKMCYP2D6NPSR1 | |
| SCHEMBL1805602 | 0.69 | CYP1A2 (0.54) | SMN1; SMN2CYP1A2PKMCYP2D6NPSR1 | |
| SCHEMBL375857 | 0.69 | CYP1A2 (0.56) | SMN1; SMN2CYP1A2PKMCYP2D6NPSR1 | |
| Solriamfetol SCHEMBL42525 | 0.69 | PKM (0.56) | SMN1; SMN2CYP1A2PKMCYP2D6NPSR1 | |
| Solriamfetol SCHEMBL30929348 | 0.69 | PKM (0.56) | SMN1; SMN2CYP1A2PKMCYP2D6NPSR1 | |
| SCHEMBL16476537 | 0.69 | CYP1A2 (0.56) | SMN1; SMN2CYP1A2PKMCYP2D6NPSR1 | |
| Solriamfetol SCHEMBL30929349 | 0.69 | PKM (0.56) | SMN1; SMN2CYP1A2PKMCYP2D6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |