Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552923 | 0.79 | CTSS (0.76) | CTSSCTSKCTSBMMP2MMP9 | |
| SCHEMBL5552921 | 0.79 | CTSS (0.76) | CTSSCTSKCTSBMMP2MMP9 | |
| SCHEMBL6601300 | 0.79 | CTSS (0.76) | CTSSCTSKCTSBMMP2MMP9 | |
| SCHEMBL7828208 | 0.77 | CTSB (0.48) | CTSSCTSKCTSBGHSRMMP9 | |
| SCHEMBL7824775 | 0.76 | GHSR (0.48) | CTSSCTSKCTSBGHSRPTPN1 | |
| SCHEMBL8483052 | 0.76 | GHSR (0.48) | CTSSCTSKCTSBGHSRPTPN1 | |
| SCHEMBL6318464 | 0.75 | CTSB (0.45) | CTSSCTSKCTSBGHSRMMP9 | |
| SCHEMBL6890928 | 0.74 | PSMB1 (0.49) | SIGMAR1MMP2 | |
| SCHEMBL6890932 | 0.74 | PSMB1 (0.49) | SIGMAR1MMP2 | |
| SCHEMBL31407327 | 0.74 | CTSB (0.49) | CTSSCTSKCTSBGHSRMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |